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折扣/货期| 货号：CDX-L0129-M020 | 规格：20 mg | 目录价：￥2226 |
产品详情
* 以下信息仅供参考，详情请以原厂网站为准
产品名称:
Lycorine hydrochloride
别名:
Lycorine chloride
产品描述:
Lycorine is an active alkaloid abundant in Amaryllidaceae with a wide range of biological properties, including antifungal, antiparasitic, antiviral, anti-inflammatory and anticancer activity. It is a protein synthesis by preventing amino acid incorporation into proteins, potentially through the inhibition of peptidyltransferases. Lycorine induces cell cycle arrest and cell death in Trichomonas. As anticancer agent on a molecular basis it induces G0/G1 phase cell cycle arrest and apoptosis, inhibits activity of histone deacetylases (HDACs), upregulates expression of p53 and p21, downregulates expression of cyclin D1 and CDK4, inhibits the Wnt/beta-catenin pathway, activates ROCK1and inhibits JAK/STAT pathways. Lycorine exhibits antiviral activities against enterovirus, flaviviruses, Zika virus, HIV-1, SARS-CoV, SARS-CoV-2 and hepatitis C virus, most probably by suppressing viral replication. Lycorine has been shown to inhibit NLRP3 inflammasome activation and pyroptosis.
宿主来源:
Plant
保存温度:
+4°C
运输温度:
Ambient
预期分子量:
323.77
产品形式:
solid
有效期:
Stable for at least 2 years after receipt when stored at +4°C.
产地:
瑞士
纯度:
>98% (HPLC)
CAS号:
2188-68-3
分子式:
C16H17NO4 . HCl
溶解度:
Soluble in water (15mg/mL), DMSO or ethanol (10mg/ml).
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