Lysine--tRNA Ligase Recombinant Protein-其他重组蛋白-深圳欣博盛生物科技有限公司

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Lysine--tRNA Ligase Recombinant Protein

品牌：ProSci LLC

官网链接

说明书

折扣/货期

货号：91-664

规格：0.05 mg

目录价：￥11969.1

产品详情

* 以下信息仅供参考，详情请以原厂网站为准

产品名称:

Lysine--tRNA Ligase Recombinant Protein

别名:

Lysine--tRNA Ligase, Lysyl-tRNA Synthetase, LysRS, KARS, KIAA0070

表达系统:

Human Cells

保存温度:

Store at -20˚C, stable for 6 months after receipt.
Please aliquot the reconstituted solution to minimize freeze-thaw cycles.

运输温度:

Dry Ice

产品形式:

Liquid

存储溶液:

Supplied as a 0.2 um filtered solution of 20mM TrisHCl,150mM NaCl,1mM DTT,20% glycerol,pH8.0. It is not recommended to reconstitute to a concentration less than 100 ug/ml.

产地:

美国

生产商:

Prosci

功能与背景:

Lysine-tRNA ligase, also known as Lysyl-tRNA synthetase, LysRS, KARS and KIAA0070, belongs to the class-II aminoacyl-tRNA synthetase family. The N-terminal cytoplasmic domain (1-65) is a functional tRNA-binding domain, which is required for nuclear localization, is involved in the interaction with DARS, but has a repulsive role in the binding to EEF1A1. A central domain (208-259) is involved in homodimerization and is required for interaction with HIV-1 GAG and incorporation into virions. KARS catalyzes the specific attachment of an amino acid to its cognate tRNA in a two step reaction: the amino acid (AA) is first activated by ATP to form AA-AMP and then transferred to the acceptor end of the tRNA. Defects in KARS are the cause of Charcot-Marie-Tooth disease recessive intermediate type B (CMTRIB).

纯度:

Greater than 95% as determined by reducing SDS-PAGE.
Endotoxin level less than 0.1 ng/ug (1 IEU/ug) as determined by LAL test.

Accession #:

Q15046

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