官网链接
折扣/货期| 货号：AG-CR1-3548-M010 | 规格：10 mg | 目录价：￥900 |
| 货号：AG-CR1-3548-M050 | 规格：50 mg | 目录价：￥3600 |
产品详情
* 以下信息仅供参考，详情请以原厂网站为准
产品名称:
m-3M3FBS
别名:
2,4,6-Trimethyl-N-[3-(trifluoromethyl)phenyl]-benzenesulfonamide
产品描述:
m-3M3FBS is a cell permeable and specific activator of phospholipase C (PLC) that has been shown to stimulate the PLC-mediated intracellular Ca2+ release, inositol phosphates production and superoxide generation in various cell types. It activates all PLC isotypes (beta2, beta3, gamma1, gamma2 and delta1) in vitro, but not heterotrimeric G proteins, PI 3-kinase or PLD. m-3M3FBS also affects calcium homeostasis independently of PLC activation. m-3M3FBS induces apoptosis in tumor cells through caspase activation, down-regulation of XIAP and intracellular calcium signaling. m-3M3FBS has been shown in vitro to trigger mitochondrial damage and activate NLRP10 (a bona fide inflammasome binding to Asc and Caspase-1) in keratinocytes. NLRP10 acts also as inflammasome in intestine epithelial cells and protects against autoinflammation in the gut.
保存温度:
+4°C
运输温度:
Ambient
预期分子量:
343.4
产品形式:
solid
产地:
瑞士
纯度:
>98%
CAS号:
200933-14-8
分子式:
C16H16F3NO2S
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