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折扣/货期| 货号：81-164 | 规格：100 ul | 目录价：￥8371.35 |
产品详情
* 以下信息仅供参考，详情请以原厂网站为准
产品名称:
MCM3 Rabbit Recombinant Antibody
别名:
HCC5; P1.h; RLFB; P1-MCM3; MCM3
反应种属:
Human, Mouse, Rat
宿主来源:
Rabbit
实验应用:
WB, IHC-P, IF/ICC, IP, ELISA
同种型:
IgG
克隆性:
Monoclonal
纯化方式:
Affinity purification
偶联:
Unconjugated
产品浓度:
Batch dependent
保存温度:
Store at -20℃. Avoid freeze / thaw cycles.
运输温度:
Blue Ice
预期分子量:
100kDa
产品形式:
Liquid
存储溶液:
Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.
产地:
美国
生产商:
Prosci
功能与背景:
The protein encoded by this gene is one of the highly conserved mini-chromosome maintenance proteins (MCM) that are involved in the initiation of eukaryotic genome replication. The hexameric protein complex formed by MCM proteins is a key component of the pre-replication complex (pre_RC) and may be involved in the formation of replication forks and in the recruitment of other DNA replication related proteins. This protein is a subunit of the protein complex that consists of MCM2-7. It has been shown to interact directly with MCM5/CDC46. This protein also interacts with and is acetylated by MCM3AP, a chromatin-associated acetyltransferase. The acetylation of this protein inhibits the initiation of DNA replication and cell cycle progression. Several transcript variants encoding different isoforms have been found for this gene.
Accession #:
P25205
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