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折扣/货期| 货号：39-102 | 规格：0.1 mg | 目录价：￥7651.8 |
产品详情
* 以下信息仅供参考，详情请以原厂网站为准
产品名称:
MERS Spike S1 Recombinant protein
表达系统:
E. coli
保存温度:
Store in working aliquots at -20˚C; For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA). Avoid freeze/thaw cycles.
运输温度:
Blue Ice
产品形式:
Liquid
存储溶液:
SARS MERS protein solution is supplied in PBS, 25mM arginine and 0.05% sodium azide.
产地:
美国
生产商:
Prosci
功能与背景:
Since April 2012, cases of the Middle East Respiratory Syndrome Coronavirus (MERS-CoV) have been identified in the following countries: Saudi Arabia, Qatar, Jordan, the United Arab Emirates, Oman, Kuwait, Yemen, Lebanon, Iran, Algeria, the United Kingdom, France, Italy, Greece, Germany, the Netherlands, Austria, Tunisia, Egypt, Malaysia, Turkey and the United States of America. Coronaviruses are the cause of the common cold, SARS (severe acute respiratory syndrome) and other severe illnesses with high mortality rates, all are classified into coronavirus family. MERS-CoV is a new type of SARS found in the coronavirus family causing severe pneumonia with sudden and serious respiratory illness with high mortality rates as well. Since January 27th 2015, the WHO has reported 956 human cases, including 351 deaths. More cases of the new coronavirus strain are expected. Like in other coronaviruses, large surface spike glycoprotein is a central structural protein of this virus; it is located above the virion surface to bind and enter into the target cell. Spike protein has 2 domains- S1 and S2. The S1 domain is responsible for cellular tropism and interaction with target cell, while the S2 domain is responsible for membrane fusion. The C-terminal of S1 domain contains a receptor binding domain, and is also a potential target for vaccine development and an antigen for diagnosis.
纯度:
>95% pure as determined by 12% PAGE (coomassie staining).
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