MHC Class I-related Protein A Recombinant Protein-其他重组蛋白-深圳欣博盛生物科技有限公司

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MHC Class I-related Protein A Recombinant Protein

品牌：ProSci LLC

官网链接

说明书

折扣/货期

货号：91-442

规格：0.05 mg

目录价：￥7581.6

产品详情

* 以下信息仅供参考，详情请以原厂网站为准

产品名称:

MHC Class I-related Protein A Recombinant Protein

别名:

MHC Class I Polypeptide-Related Sequence A, MIC-A, MICA, PERB11.1

表达系统:

Human Cells

保存温度:

Lyophilized protein should be stored at -20˚C, though stable at room temperature for 3 weeks.
Reconstituted protein solution can be stored at 4-7˚C for 2-7 days.
Aliquots of reconstituted samples are stable at -20˚C for 3 months.

运输温度:

Blue Ice

产品形式:

Lyophilized

存储溶液:

Lyophilized from a 0.2 um filtered solution of 20mM PB, 150mM NaCl, pH 7.2. It is not recommended to reconstitute to a concentration less than 100 ug/ml. Dissolve the lyophilized protein in ddH2O.

产地:

美国

生产商:

Prosci

功能与背景:

MHC Class I Polypeptide-Related Sequence A (MICA) is a transmembrane glycoprotein that functions as a ligand for human NKG2D. Unlike classical MHC class I molecules, MICA does not form a heterodimer with beta-2-microglobulin. MICA shares 85% amino acid identity with a closely related protein, MICB. MICA acts as a stress-induced self-antigen that is recognized by NK cells, NKT cells, and most of the subtypes of T cells. As a Ligand for the KLRK1/NKG2D receptor, MICA binds to KLRK1 leads to cell lysis. MICA functions as an antigen for gamma delta T cells and is frequently expressed in epithelial tumors. MICA antigens are able to elicit the synthesis of alloantibodies in transplant recipients. Studies have shown that anti-MICA antibodies are associated with acute renal allograft rejection and failure. MICA recognition is involved in tumor surveillance, viral infections, and autoimmune diseases.

纯度:

Greater than 95% as determined by reducing SDS-PAGE.
Endotoxin level less than 0.1 ng/ug (1 IEU/ug) as determined by LAL test.

Accession #:

Q29983

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