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折扣/货期| 货号：AG-CP3-0026-M001 | 规格：1 mg | 目录价：￥600 |
| 货号：AG-CP3-0026-M005 | 规格：5 mg | 目录价：￥1440 |
产品详情
* 以下信息仅供参考，详情请以原厂网站为准
产品名称:
MOTS-c (human)
别名:
H-Met-Arg-Trp-Gln-Glu-Met-Gly-Tyr-Ile-Phe-Tyr-Pro-Arg-Lys-Leu-Arg-OH . TFA; Mitochondrial Open Reading Frame of the 12S rRNA-c; MOTS3
产品描述:
Mitochondria-derived peptide (MDP). Promotes biosynthesis of the endogenous AMP analog AICAR and consequently AMP-activated protein kinase (AMPK). Induces cellular and systemic glucose uptake and improves insulin sensitivity. Shown to prevent diet-induced obesity (DIO) in mice. Potential anti-obesity and anti-aging compound. Involved in cellular stress resistance by regulating the nuclear genome. During metabolic stress (serum or glucose deprivation or oxidative stress) translocates to the nucleus in an AMPK-dependent manner. In the nucleus, MOTS-c binds to the transcription factor NRF2 that is a stress-responsive transcription factor and activates anti-oxidative stress genes.
宿主来源:
Synthetic.
保存温度:
+4°C
运输温度:
Ambient
预期分子量:
2174.6 . 114.0
产品形式:
solid
产地:
瑞士
纯度:
>95% (HPLC)
CAS号:
1627580-64-6
分子式:
C101H152N28O22S2 . C2HF3O2
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