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折扣/货期| 货号：GTX23373 | 规格：250μl | 目录价：￥5000 |
产品详情
* 以下信息仅供参考，详情请以原厂网站为准
产品名称:
MRP2 antibody [M2III-6]
别名:
ATP binding cassette subfamily C member 2 , ABC30 , CMOAT , DJS , MRP2 , cMRP
反应种属:
Human, Rat
宿主来源:
Mouse
实验应用:
ICC/IF, IHC-Fr, IHC-P, WB
靶标/特异性:
This antibody detects MRP 2. It does not cross-react with human MDR 1, MRP 1, MRP 3 or MRP 5 gene products.
同种型:
IgG2a
免疫原:
Bacterial fusion protein of human MRP 2 containing the carboxy-terminal region (202-)
克隆性:
Monoclonal
克隆号:
M2III-6
偶联:
Unconjugated
产品浓度:
0.1 mg/ml (Please refer to the vial label for the specific concentration.)
保存温度:
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage 1-2 weeks, store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
运输温度:
4°C
产品形式:
Liquid
存储溶液:
PBS, 1% BSA, 0.1% Sodium azide.
生产商:
GeneTex
功能与背景:
The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MRP subfamily which is involved in multi-drug resistance. This protein is expressed in the canalicular (apical) part of the hepatocyte and functions in biliary transport. Substrates include anticancer drugs such as vinblastine; therefore, this protein appears to contribute to drug resistance in mammalian cells. Several different mutations in this gene have been observed in patients with Dubin-Johnson syndrome (DJS), an autosomal recessive disorder characterized by conjugated hyperbilirubinemia. [provided by RefSeq, Jul 2008]
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