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折扣/货期| 货号：GTX23294 | 规格：500μl | 目录价：￥5000 |
产品详情
* 以下信息仅供参考，详情请以原厂网站为准
产品名称:
NOTCH1 antibody [A6]
别名:
notch receptor 1 , AOS5 , AOVD1 , TAN1 , hN1
反应种属:
Human, Mouse
宿主来源:
Mouse
实验应用:
FCM, IHC-P
靶标/特异性:
This antibody has not been tested for its cross reactivity with Notch 2.
同种型:
IgG2b
免疫原:
Recombinant protein encoding the ligand binding region of human Notch 1
克隆性:
Monoclonal
克隆号:
A6
纯化方式:
Protein A affinity purified
偶联:
Unconjugated
产品浓度:
0.2 mg/ml (Please refer to the vial label for the specific concentration.)
保存温度:
Store as concentrated solution. Centrifuge briefly prior to opening vial. Store at 4ºC. DO NOT FREEZE.
运输温度:
4°C
产品形式:
Liquid
存储溶液:
PBS, 0.2% BSA, 0.1% Sodium azide.
生产商:
GeneTex
功能与背景:
This gene encodes a member of the NOTCH family of proteins. Members of this Type I transmembrane protein family share structural characteristics including an extracellular domain consisting of multiple epidermal growth factor-like (EGF) repeats, and an intracellular domain consisting of multiple different domain types. Notch signaling is an evolutionarily conserved intercellular signaling pathway that regulates interactions between physically adjacent cells through binding of Notch family receptors to their cognate ligands. The encoded preproprotein is proteolytically processed in the trans-Golgi network to generate two polypeptide chains that heterodimerize to form the mature cell-surface receptor. This receptor plays a role in the development of numerous cell and tissue types. Mutations in this gene are associated with aortic valve disease, Adams-Oliver syndrome, T-cell acute lymphoblastic leukemia, chronic lymphocytic leukemia, and head and neck squamous cell carcinoma. [provided by RefSeq, Jan 2016]
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