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折扣/货期| 货号：V9204-100UG | 规格：100 ug | 目录价：￥6652.1 |
| 货号：V9204-20UG | 规格：20 ug | 目录价：￥3082.1 |
产品详情
* 以下信息仅供参考，详情请以原厂网站为准
产品名称:
MXI1 Antibody / Max-interacting protein 1 / BHLHC11
产品描述:
It is now well established that Myc regulation of cell proliferation and differentiation involves a family of related transcription factors. One such factor, Max, is an obligate heterodimeric partner for Myc and can also form heterodimers with at least four related proteins designated Mad 1, Mxi1 (also designated Mad 2), Mad 3 and Mad 4. Like Mad 1 and Mxi1, association of Mad 3 and Mad 4 with Max results in transcriptional repression. Both Myc and the Mad proteins have short half-lives and their synthesis is tightly regulated, while Max expression is constitutive and relatively stable. Two related mammalian cDNAs have been identified and shown to encode Mad- binding proteins. Both possess sequence homology with the yeast transcription repressor Sin3 including four conserved paired amphipathic helix (PAH) domains. mSin3A and mSin3B specifically interact with the Mad proteins via their second paired amphipathic helix domain (PAH2). It has been suggested that Mad-Max heterodimers repress transcription by tethering mSin3 to DNA as corepressors.
反应种属:
Human
宿主来源:
Mouse
实验应用:
FACS, IF, WB
同种型:
Mouse IgG2b
免疫原:
Recombinant full-length human MXI1 protein was used as the immunogen for the MXI1 antibody.
克隆性:
Monoclonal (mouse origin)
克隆号:
PCRP-MXI1-1A3
纯化方式:
Protein A/G affinity
保存温度:
Aliquot the MXI1 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
产品形式:
Purified
存储溶液:
0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced), 0.05% sodium azide
产地:
美国
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