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折扣/货期| 货号：GTX11095 | 规格：50μl | 目录价：￥5000 |
产品详情
* 以下信息仅供参考，详情请以原厂网站为准
产品名称:
MYO6 antibody [MUD-19]
别名:
myosin VI , DFNA22 , DFNB37 , Myo6-007 , Myo6-008
反应种属:
Human, Mouse, Rat
宿主来源:
Mouse
实验应用:
ELISA, IHC, IP, WB
同种型:
IgG1
免疫原:
synthetic peptide corresponding to amino acids 291-302 of human myosin VI.
克隆性:
Monoclonal
克隆号:
MUD-19
纯化方式:
Purified immunoglobulin
偶联:
Unconjugated
产品浓度:
~1 mg/ml (Please refer to the vial label for the specific concentration.)
保存温度:
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
运输温度:
4°C
产品形式:
Liquid
存储溶液:
PBS, 1% BSA, 15mM Sodium azide.
生产商:
GeneTex
功能与背景:
Myosins belong to a superfamily of actin based motor proteins comprising at least 15 or more classes. There are two main groups of myosins: the conventional (class II) and the unconventional myosins. Myosin VI is a relatively abundant widespread unconventional myosin composed of an N-terminal motor domain, a light chain binding neck region, a coil-coiled region, and a highly conserved C-terminal domain. At the _x005f_x0018_converter_x005f_x0019_ region between the catalytic head and the neck region of myosin VI, there is a characteristic linker of approximately 50 amino acids. Native myosin VI is apparently a two-headed dimer of the heavy chains with each heavy chain bound to calmodulin light chain. Myosin VI is a unique _x005f_x0018_reverse_x005f_x0019_ actin motor in vitro i.e. to display motility towards the pointed (minus) ends of actin filaments, a direction opposite to all other currently known myosins.
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