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折扣/货期| 货号：CDX-S0019-M025 | 规格：25 mg | 目录价：￥1260 |
| 货号：CDX-S0019-M100 | 规格：100 mg | 目录价：￥3878 |
产品详情
* 以下信息仅供参考，详情请以原厂网站为准
产品名称:
N-Succinimidyl 3-(2-pyridyldithio)propionate
别名:
3-(2-Pyridyldithio)propionic acid N-hydroxysuccinimide ester; SPDP
产品描述:
N-Succinimidyl 3-(2-pyridyldithio)propionate is a heterobifunctional cross-linking reagent with amine and sulfhydryl reactivity. It is typically coupled initially to molecules containing primary amines by amide bonds buffered at pH 7.5 (6.5-8.5). Second coupling specific for molecules containing free sulfhydryl by thiol-disulfide exchange buffered at pH 8.0 (7.5-8.5). Alternately, this reagent may be used as a protected thiolating reagent following initial coupling and reduction of linker. It incorporates four atom linker. N-Succinimidyl 3-(2-pyridyldithio)propionate (SPDP) is useful for the preparation of enzyme immunoconjugates and hapten carrier molecule conjugates. It has been used for antibody conjugation and as a protein cross-linker. It is also a glutathione cleavable ADC linker used for the antibody-drug conjugates (ADCs).
宿主来源:
Synthetic
保存温度:
+4°C
运输温度:
Ambient
预期分子量:
312.36
产品形式:
solid
有效期:
Stable for at least 2 years after receipt when stored at -20°C.
产地:
瑞士
纯度:
>97% (NMR)
CAS号:
68181-17-9
分子式:
C12H12N2O4S2
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