货号:CDX-N0125-M500 | 规格:500 mg | 目录价:¥1596 |
货号:CDX-N0125-G001 | 规格:1 g | 目录价:¥2744 |
产品详情
* 以下信息仅供参考,详情请以原厂网站为准
产品名称:
Naphthol AS-E phosphate
别名:
N-(4-Chlorophenyl)-3-(phosphonooxy)naphthalene-2-carboxamide; KG-501; NASEP
产品描述:
Histochemical substrate for alkaline phosphatases. Aldolase inhibitor. Small molecule inhibitor. Anticancer compound that directly targets the KIX domain of CBP, resulting in a disrupted CREB-CBP complex, inhibited CREB-target gene induction and inhibited IL-1beta-mediated angiogenic activity in cancer cell lines. Inhibits activity of transcription factor Myb by blocking interaction with KIX domain of coactivator p300 in human leukemia cells. Interferes with the Myb–KIX interaction in vitro and inhibits Myb activity in vivo. Suppresses the expression of Myb target genes and induces myeloid differentiation and apoptosis.
宿主来源:
Synthetic.
保存温度:
+4°C
运输温度:
Ambient
预期分子量:
377.72
产品形式:
solid
有效期:
Stable for at least 2 years after receipt when stored at -20°C.
产地:
瑞士
纯度:
>99% (HPLC)
CAS号:
18228-17-6
分子式:
C17H13ClNO5P
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