Neprilysin Recombinant Protein-其他重组蛋白-深圳欣博盛生物科技有限公司

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Neprilysin Recombinant Protein

品牌：ProSci LLC

官网链接

说明书

折扣/货期

货号：96-540

规格：0.05 mg

目录价：￥11547.9

产品详情

* 以下信息仅供参考，详情请以原厂网站为准

产品名称:

Neprilysin Recombinant Protein

别名:

MME, CALLA, CD10, DKFZp686O16152, MGC126681, MGC126707, NEP, SFE, Neprilysin

实验应用:

表达系统:

HEK293 cells

保存温度:

Lyophilized Protein should be stored at -20˚C or lower for long term storage. Upon reconstitution, working aliquots should be stored at -20˚C or -70˚C. Avoid repeated freeze-thaw cycles.

运输温度:

Blue Ice

产品形式:

Lyophilized

存储溶液:

20 mM Tris, 100 mM NaCl, pH8.0

产地:

美国

生产商:

Prosci

功能与背景:

Cluster of differentiation 10 (CD10) is also known as membrane metallo-endopeptidase, neutral endopeptidase (NEP), Neprilysin, and common acute lymphoblastic leukemia antigen (CALLA), is a 90-110-kDa type II transmembrane glycoprotein normally expressed by a variety of tissues, including epithelial cells of the prostate, kidney, intestine, endometrium, adrenal glands, and lung. This zinc-dependent metalloprotease enzyme cleaves peptide bonds on the amino side of hydrophobic residues and inactivates a variety of physiologically active secreted peptides. CD20 is thought to be the rate-limiting degrading enzyme of amyloid β peptide (Aβ) whose abnormal misfolding and aggregation in neural tissue has been implicated in the development of Alzheimer's disease (AD). CD10 is also identified as the common acute lymphoblastic leukemia antigen (CALLA) present on leukemic cells of pre-B phenotype, and thus serves as the most important biomarker in the diagnosis of human acute lymphocytic leukemia (ALL).

纯度:

>95% as determined by SDS-PAGE.

Accession #:

NP_000893.2

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