| 货号:40-442-0.005 mg | 规格:0.005 mg | 目录价:¥3783 |
| 货号:40-442-0.025 mg | 规格:0.025 mg | 目录价:¥5674.5 |
产品详情
* 以下信息仅供参考,详情请以原厂网站为准
产品名称:
Neuropoietin Recombinant Protein
别名:
NP, Gm494, Cardiotrophin-2, Neuropoietin, CT-2
表达系统:
E. coli
保存温度:
The lyophilized Neuropoietin recombinant protein is stable for at least 2 years from date of receipt at -20˚C. Reconstituted Neuropoietin is stable for at least 3 months when stored in working aliquots with a carrier protein at -20˚C. As with any protein, exposing Neuropoietin recombinant protein to repeated freeze / thaw cycles is not recommended. When working with proteins care should be taken to keep recombinant protein at a cool and stable temperature.
运输温度:
Blue Ice
产品形式:
Lyophilized
产地:
美国
生产商:
Prosci
功能与背景:
Neuropoietin is a newly identified member of the IL-6 cytokine family. Members of this family, including IL-6, IL-11, oncostatin M, leukemia inhibitory factor (LIF), cardiotrophin-1 (CT-1), cardiotrophin-like cytokine, and CNTF, display a four-helix bundle structure, and signal through gp130-containing receptor complexes. Neuropoietin, which is predominantly expressed in neuroepithelia during embryonic life, acts through a receptor complex comprising CNTF receptor-a component, gp 130, and LIF receptor. Like CNTF, it promotes the survival of embryonic motor neurons and could increase the proliferation of neural precursor cells in the presence of EGF and FGF-2. Interestingly, the human Neuropoietin gene has evolved toward a pseudogene, suggesting that the alternative signaling via CNTF is an effective compensatory pathway. Recombinant murine Neuropoietin is a 19.8 kDa protein containing 183 amino acid residues.
纯度:
Greater than 98% by SDS-PAGE gel and HPLC analyses.
Endotoxin level is less than 0.1 ng per μg (1EU/μg).
Endotoxin level is less than 0.1 ng per μg (1EU/μg).
生物活性:
The ED50 was determined by the dose - dependent stimulation of the proliferation of human TF - 1 cells is 0.5 - 0.8 μg/mL.
Accession #:
NP_942155.1
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