| 货号:40-500-0.005 mg | 规格:0.005 mg | 目录价:¥3783 |
| 货号:40-500-0.02 mg | 规格:0.02 mg | 目录价:¥5674.5 |
产品详情
* 以下信息仅供参考,详情请以原厂网站为准
产品名称:
Neurturin Recombinant Protein
别名:
NTN, Neurturin
表达系统:
E. coli
保存温度:
The lyophilized Neurturin recombinant protein is stable for at least 2 years from date of receipt at -20˚C. Reconstituted Neurturin is stable for at least 3 months when stored in working aliquots with a carrier protein at -20˚C. As with any protein, exposing Neurturin recombinant protein to repeated freeze / thaw cycles is not recommended. When working with proteins care should be taken to keep recombinant protein at a cool and stable temperature.
运输温度:
Blue Ice
产品形式:
Lyophilized
产地:
美国
生产商:
Prosci
功能与背景:
Neurturin is a disulfide-linked homodimer neurotrophic factor structurally related to GDNF, Artemin, and Persephin. These proteins belong to the cysteine-knot family of growth factors that assume stable dimeric structures. Neurturin signals through a multicomponent receptor system, composed of RET and one of four GFR alpha (alpha1-alpha4) receptors. Neurturin promotes the development and survival of sympathetic and sensory neurons by signaling through a receptor system composed of RET and GFRalpha2. The functional form of human Neurturin is a disulfide-linked homodimer, of two 11.8 kDa polypeptide monomers (206 total amino acid residues). Each monomer contains seven conserved cysteine residues, one of which (Cys 69) is used for inter-chain disulfide bridging and the others are involved in intramolecular ring formation known as the cysteine knot configuration.
纯度:
Greater than 98% by SDS-PAGE gel and HPLC analyses.
Endotoxin level is less than 0.1 ng per μg (1EU/μg).
Endotoxin level is less than 0.1 ng per μg (1EU/μg).
生物活性:
Human Neurturin at a concentration of 100 ng/mL will support the survival of 65% of newborn rat sympathetic neurons.
Accession #:
NP_004549.1
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