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折扣/货期| 货号：GTX80359 | 规格：50μl | 目录价：￥7600 |
产品详情
* 以下信息仅供参考，详情请以原厂网站为准
产品名称:
ORC2 antibody [3G6]
别名:
origin recognition complex subunit 2 , ORC2L
反应种属:
Human
宿主来源:
Rat
实验应用:
IP, WB
靶标/特异性:
Human ORC2
同种型:
IgG2a
免疫原:
ORC2 (hsORC)
克隆性:
Monoclonal
克隆号:
3G6
纯化方式:
Protein G
偶联:
Unconjugated
产品浓度:
1 mg/ml (Please refer to the vial label for the specific concentration.)
保存温度:
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
运输温度:
4°C
预期分子量:
66
产品形式:
Liquid
存储溶液:
PBS, 0.1% Sodium azide.
生产商:
GeneTex
功能与背景:
The origin recognition complex (ORC) is a highly conserved six subunits protein complex essential for the initiation of the DNA replication in eukaryotic cells. Studies in yeast demonstrated that ORC binds specifically to origins of replication and serves as a platform for the assembly of additional initiation factors such as Cdc6 and Mcm proteins. The protein encoded by this gene is a subunit of the ORC complex. This protein forms a core complex with ORC3, -4, and -5. It also interacts with CDC45 and MCM10, which are proteins known to be important for the initiation of DNA replication. This protein has been demonstrated to specifically associate with the origin of replication of Epstein-Barr virus in human cells, and is thought to be required for DNA replication from viral origin of replication. Alternatively spliced transcript variants have been found, one of which is a nonsense-mediated mRNA decay candidate. [provided by RefSeq, Oct 2010]
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