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折扣/货期| 货号：AG-CR1-3592-M005 | 规格：5 mg | 目录价：￥240 |
| 货号：AG-CR1-3592-M025 | 规格：25 mg | 目录价：￥600 |
| 货号：AG-CR1-3592-M100 | 规格：100 mg | 目录价：￥1380 |
产品详情
* 以下信息仅供参考，详情请以原厂网站为准
产品名称:
Oxaliplatin
别名:
1-OHP; ACT 078; RP 54780; NSC 266046; Diaminocyclohexane oxalatoplatinum
产品描述:
Potent platinum-based antineoplastic agent with wide spectrum anticancer activity [2, 7-9]. Anticancer compound. Forms inter- and intrastrand DNA adducts/crosslinks, consequently blocking DNA replication and transcription and inducing cell death [1, 4, 7, 10, 13]. Shows antitumor activity in cisplatin resistant cell lines [3, 8]. Shows better biochemical, pharmacological and cytotoxic properties than cisplatin (Prod. No. AG-CR1-3590) and carboplatin (Prod. No. AG-CR1-3591) [5, 7, 8]. Apoptosis inducer [10, 11]. Targets other proteins and enzymes [6]. Anticancer activity and antitumor specificity depends on selective uptake through human organic cation transporters 1 (OCT1) and OCT2 [12]. Neurotoxic profile depends on organic cation transporter 2 (OCT2) uptake [14].
保存温度:
+4°C
运输温度:
Ambient
预期分子量:
397.3
产品形式:
solid
有效期:
Stable for at least 2 years after receipt when stored at -20°C.
产地:
瑞士
纯度:
>98% (1H-NMR)
CAS号:
61825-94-3
分子式:
C8H14N2O4Pt
溶解度:
Soluble in DMSO (20mg/ml)* or water (2mg/ml). Slightly soluble in methanol. Insoluble in ethanol.
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