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折扣/货期| 货号：81-281 | 规格：100 ul | 目录价：￥8371.35 |
产品详情
* 以下信息仅供参考，详情请以原厂网站为准
产品名称:
PABPN1 Rabbit Recombinant Antibody
别名:
OPMD; PAB2; PABII; PABP2; PABP-2; PABPN1
反应种属:
Human, Mouse, Rat
宿主来源:
Rabbit
实验应用:
WB, IF/ICC, IF-P, IHC-P, ELISA
同种型:
IgG
克隆性:
Monoclonal
纯化方式:
Affinity purification
偶联:
Unconjugated
产品浓度:
Batch dependent
保存温度:
Store at -20℃. Avoid freeze / thaw cycles.
运输温度:
Blue Ice
预期分子量:
50kDa
产品形式:
Liquid
存储溶液:
Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.
产地:
美国
生产商:
Prosci
功能与背景:
This gene encodes an abundant nuclear protein that binds with high affinity to nascent poly(A) tails. The protein is required for progressive and efficient polymerization of poly(A) tails at the 3' ends of eukaryotic transcripts and controls the size of the poly(A) tail to about 250 nt. At steady-state, this protein is localized in the nucleus whereas a different poly(A) binding protein is localized in the cytoplasm. This gene contains a GCG trinucleotide repeat at the 5' end of the coding region, and expansion of this repeat from the normal 6 copies to 8-13 copies leads to autosomal dominant oculopharyngeal muscular dystrophy (OPMD) disease. Related pseudogenes have been identified on chromosomes 19 and X. Read-through transcription also exists between this gene and the neighboring upstream BCL2-like 2 (BCL2L2) gene.
Accession #:
Q86U42
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