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折扣/货期| 货号：CDX-P0662-M001 | 规格：1 mg | 目录价：￥4872 |
产品详情
* 以下信息仅供参考，详情请以原厂网站为准
产品名称:
PBFI
别名:
Potassium-binding Benzofuran Isophthalate
产品描述:
PBFI is a cell-impermeant fluorescent indicator for potassium ions, suitable for detection of physiological concentrations of K+ in the presence of other monovalent cations. PBFI is used to measure intracellular potassium (K+) fluxes in animal cells and in plant cells and vacuoles. The observation that intracellular K+ levels are a controlling factor in apoptotic cell death pathways, increased the interest for PBFI. PBFI has been used for detecting adrenoceptor-stimulated decreases of intracellular K+ concentration in astrocytes and neurons, evaluating the mediating effects of K+ depletion on monocytic cell necrosis, measuring intracellular K+ fluxes associated with apoptotic cell shrinkage, monitoring mitochondrial KATP channel activation, or detecting elevated intracellular K+ levels associated with HIV-induced cytopathology. Flow cytometric measurements using UV argon-ion laser excitation (351nm and 364nm) of PBFI indicate that K+ efflux induces shrinkage of apoptotic cells and is a trigger for caspase activation. Spectral data: lambdaex 336nm;, lambdaem 557nm.
保存温度:
-20°C
运输温度:
Ambient
预期分子量:
882.86
产品形式:
solid
有效期:
Stable for at least 2 years after receipt when stored at -20°C.
产地:
瑞士
纯度:
~80% (HPLC)
CAS号:
124549-11-7
分子式:
C46H46N2O16
溶解度:
Soluble in methanol or DMSO.
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