PBFI-其他小分子化合物-深圳欣博盛生物科技有限公司

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PBFI

品牌：Adipogen

官网链接

说明书

折扣/货期

货号：CDX-P0662-M001

规格：1 mg

目录价：￥5054

产品详情

* 以下信息仅供参考，详情请以原厂网站为准

产品名称:

PBFI

别名:

Potassium-binding Benzofuran Isophthalate

产品描述:

PBFI is a cell-impermeant fluorescent indicator for potassium ions, suitable for detection of physiological concentrations of K+ in the presence of other monovalent cations. PBFI is used to measure intracellular potassium (K+) fluxes in animal cells and in plant cells and vacuoles. The observation that intracellular K+ levels are a controlling factor in apoptotic cell death pathways, increased the interest for PBFI. PBFI has been used for detecting adrenoceptor-stimulated decreases of intracellular K+ concentration in astrocytes and neurons, evaluating the mediating effects of K+ depletion on monocytic cell necrosis, measuring intracellular K+ fluxes associated with apoptotic cell shrinkage, monitoring mitochondrial KATP channel activation, or detecting elevated intracellular K+ levels associated with HIV-induced cytopathology. Flow cytometric measurements using UV argon-ion laser excitation (351nm and 364nm) of PBFI indicate that K+ efflux induces shrinkage of apoptotic cells and is a trigger for caspase activation. Spectral data: lambdaex 336nm;, lambdaem 557nm.

保存温度:

-20°C

运输温度:

Ambient

预期分子量:

882.86

产品形式:

solid

产地:

瑞士

纯度:

~80% (HPLC)