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折扣/货期| 货号：SD8500 | 规格：1 Set | 目录价：￥3934 |
产品详情
* 以下信息仅供参考，详情请以原厂网站为准
产品名称:
PDL1 Detection Set
反应种属:
Human
宿主来源:
llama
实验应用:
ELISA,Flow,ICC,IF
同种型:
sdab
克隆性:
Monoclonal
纯化方式:
PD-L1 Antibodies are affinity chromatography purified via Nickel column.Antibodies are supplied as a His-tagged purified protein. They also contains a myc-tag for detection.
偶联:
Unconjugated
产品浓度:
Antibody 1 mg/mL
保存温度:
PD-L1 antibodies should be stored in working aliquots at -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
运输温度:
Dry Ice
产品形式:
Liquid
存储溶液:
PBS containing 0.02% sodium azide.
产地:
美国
生产商:
Prosci
功能与背景:
Cell-mediated immune responses are initiated by T lymphocytes that are themselves stimulated by cognate peptides bound to MHC molecules on antigen-presenting cells (APC). T-cell activation is generally self-limited as activated T cells express receptors such as PD-1 (also known as PDCD-1) that mediate inhibitory signals from the APC. PD-1 can bind two different but related ligands, PD-L1 and PD-L2. PD-L1 is a B7-related protein that inhibits cell-mediated immune responses by reducing the secretion of IL-2 and IL-10 from memory T cells. This suggests that PD-L1 may be useful in reducing allogenic CD4+ memory T-cell responses to endothelial cells, thereby reducing the likelihood of host immune responses to allografts.
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