PDL1 Detection Set -其他-深圳欣博盛生物科技有限公司

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PDL1 Detection Set

品牌：Prosci

官网链接

说明书

折扣/货期

货号：SD8500

规格：1 Set

目录价：￥3934.125

产品详情

* 以下信息仅供参考，详情请以原厂网站为准

产品名称:

PDL1 Detection Set

反应种属:

Human

宿主来源:

llama

实验应用:

ELISA,Flow,ICC,IF

同种型:

sdab

克隆性:

Monoclonal

纯化方式:

PD-L1 Antibodies are affinity chromatography purified via Nickel column.Antibodies are supplied as a His-tagged purified protein. They also contains a myc-tag for detection.

偶联:

Unconjugated

产品浓度:

Antibody 1 mg/mL

保存温度:

PD-L1 antibodies should be stored in working aliquots at -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

运输温度:

Dry Ice

产品形式:

Liquid

存储溶液:

PBS containing 0.02% sodium azide.

产地:

美国

生产商:

Prosci

功能与背景:

Cell-mediated immune responses are initiated by T lymphocytes that are themselves stimulated by cognate peptides bound to MHC molecules on antigen-presenting cells (APC). T-cell activation is generally self-limited as activated T cells express receptors such as PD-1 (also known as PDCD-1) that mediate inhibitory signals from the APC. PD-1 can bind two different but related ligands, PD-L1 and PD-L2. PD-L1 is a B7-related protein that inhibits cell-mediated immune responses by reducing the secretion of IL-2 and IL-10 from memory T cells. This suggests that PD-L1 may be useful in reducing allogenic CD4+ memory T-cell responses to endothelial cells, thereby reducing the likelihood of host immune responses to allografts.

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