| 货号:SD8600 | 规格:1 Set | 目录价:¥6420.375 |
产品详情
* 以下信息仅供参考,详情请以原厂网站为准
产品名称:
PD1 Detection Set
反应种属:
Human
宿主来源:
llama
实验应用:
ELISA
同种型:
sdab
克隆性:
Monoclonal
纯化方式:
PD-1 Antibodies are affinity chromatography purified via Nickel column. Antibodies are supplied as a His-tagged purified protein. They also contains a myc-tag for detection.
偶联:
Unconjugated
产品浓度:
Antibody 1 mg/mL
保存温度:
PD-1 antibodies should be stored in working aliquots at -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
运输温度:
Dry Ice
产品形式:
Liquid
存储溶液:
PD-1 Antibodies are supplied in PBS.
产地:
美国
生产商:
Prosci
功能与背景:
PD-1 Antibody: Cell-mediated immune responses are initiated by T lymphocytes that are themselves stimulated by cognate peptides bound to MHC molecules on antig en-presenting cells (APC). T-cell activation is generally self-limited as activated T cells express receptors such as PD-1 (also known as PDCD-1) that mediate inhibitory signals from the APC. PD-1 can bind two different but related ligands, PDL-1 and PDL-2. Upon binding to either of these ligands, signals generated by PD-1 inhibit the activation of the immune response in the absence of "danger signals" such as LPS or other molecules associated with bacteria or other pathogens. Evidence for this is seen in PD1-null mice who exhibit hyperactivated immune systems and autoimmune diseases.
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