| 货号:SYN-1141-M001 | 规格:1 mg | 目录价:¥1204 |
| 货号:SYN-1141-M005 | 规格:5 mg | 目录价:¥1820 |
| 货号:SYN-1141-M010 | 规格:10 mg | 目录价:¥3178 |
| 货号:SYN-1141-M050 | 规格:50 mg | 目录价:¥10808 |
| 货号:SYN-1141-M100 | 规格:100 mg | 目录价:¥询价 |
产品详情
* 以下信息仅供参考,详情请以原厂网站为准
产品名称:
Pelitinib
别名:
EKB-569
产品描述:
Pelitinib, also known as EKB 569, is a potent, irreversible inhibitor of the EGFR tyrosine kinase. Cell based IC(50) values range from 39nM to 80nM and in vitro kinase assays are in sub-nanomolar range for EGFR receptors. In xenograft tumor models using overexpressing A431 cells Pelitinib inhibits growth of tumors with effective doses of 3.5-10mg/kg/dl. Recent research also shows that Pelitinib can potentiate radiation induced killing of squamouse cell carcinoma via the inhibition of IR-induced NF-kappaB mediated cell survial pathway.
保存温度:
+4°C
运输温度:
Ambient
预期分子量:
467.9
产品形式:
solid
产地:
瑞士
纯度:
>95%
CAS号:
257933-82-7
分子式:
C24H23ClFN5O2
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