货号:SYN-1064-M001 | 规格:1 mg | 目录价:¥1204 |
货号:SYN-1064-M005 | 规格:5 mg | 目录价:¥2268 |
货号:SYN-1064-M010 | 规格:10 mg | 目录价:¥3332 |
货号:SYN-1064-M050 | 规格:50 mg | 目录价:¥9828 |
货号:SYN-1064-M100 | 规格:100 mg | 目录价:¥询价 |
产品详情
* 以下信息仅供参考,详情请以原厂网站为准
产品名称:
PF-562271
别名:
PF562271
产品描述:
PF-562,271 is a potent, ATP-competitive, reversible inhibitor of FAK and Pyk2 catalytic activity with a IC(50) of 1.5 and 14nM, respectively. In addition, PF-562,271 displayed robust inhibition in an inducible cell-based assay measuring phospho-FAK with an IC(50) of 5nM. PF-562,271 was evaluated against multiple kinases and displays >100x selectivity against a long list of nontarget kinases. In tests, PF-562,271 inhibits FAK phosphorylation in vivo in a dose-dependent fashion with a calculated EC50 of 93ng/mL using injections.
保存温度:
+4°C
运输温度:
Ambient
预期分子量:
507.5
产品形式:
solid
有效期:
Stable for at least 2 years after receipt when stored at -20°C.
产地:
瑞士
纯度:
>95%
CAS号:
717907-75-0
分子式:
C21H20F3N7O3S
溶解度:
Soluble in DMSO or ethanol.
促销活动
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