PK150 (Sorafenib Analog)-其他小分子化合物-深圳欣博盛生物科技有限公司

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PK150 (Sorafenib Analog)

品牌：Adipogen

官网链接

说明书

折扣/货期

货号：AG-CR1-0162-M001	规格：1 mg	目录价：￥240
货号：AG-CR1-0162-M005	规格：5 mg	目录价：￥420
货号：AG-CR1-0162-M025	规格：25 mg	目录价：￥1440

产品详情

* 以下信息仅供参考，详情请以原厂网站为准

产品名称:

PK150 (Sorafenib Analog)

别名:

Antibiotic PK150; 1-(4-Chloro-3-(trifluoromethyl)phenyl)-3-(2,2-difluorobenzo[d][1,3]dioxol-5-yl)urea

产品描述:

Analog of the anticancer drug sorafenib. PK150 is a potent antibiotic. It shows oral bioavailability and antibacterial activity against several pathogenic strains at submicromolar concentrations. PK150 inhibits Gram-positive Methicillin-sensitive S. aureus (MSSA), Methicillin-resistant S. aureus (MRSA), Vancomycin intermediate S. aureus (VISA) with MICs of 0.3, 0.3-1, 0.3 µM, respectively. PK150 did not induce in vitro resistance and shows oral bioavailability and in vivo efficacy. The mode of action includes the interference with menaquinone biosynthesis by inhibiting demethylmenaquinone methyltransferase and the stimulation of protein secretion by altering the activity of signal peptidase IB.

保存温度:

+4°C

运输温度:

Ambient

预期分子量:

394.7

产品形式:

solid

产地:

瑞士

纯度:

>98% (HPLC)