PLA2G1B Recombinant Protein-其他重组蛋白-深圳欣博盛生物科技有限公司

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PLA2G1B Recombinant Protein

品牌：ProSci LLC

官网链接

说明书

折扣/货期

货号：92-417

规格：0.05 mg

目录价：￥11969.1

产品详情

* 以下信息仅供参考，详情请以原厂网站为准

产品名称:

PLA2G1B Recombinant Protein

别名:

PLA2G1B/Phospholipase A2/Group IB phospholipase A2/PLA2/PLA2A/PPLA2, PLA2, PLA2A

表达系统:

Human Cells

保存温度:

Store at -20˚C, stable for 6 months after receipt.
Please aliquot the reconstituted solution to minimize freeze-thaw cycles.

运输温度:

Dry Ice

产品形式:

Liquid

存储溶液:

Supplied as a 0.2 um filtered solution of 20mM TrisHCl,150mM NaCl,10% Glycerol,pH8.0. It is not recommended to reconstitute to a concentration less than 100 ug/ml.

产地:

美国

生产商:

Prosci

功能与背景:

Phospholipase A2(PLA2G1B) is a secreted protein which belongs to the phospholipase A2 family. It catalyzes the release of fatty acids from glycero-3-phosphocholines. It catalyzes the calcium-dependent hydrolysis of the 2-acyl groups in 3-sn-phosphoglycerides. This releases glycerophospholipids and arachidonic acid that serve as the precursors of signal molecules. Sequences of pancreatic PLA2G1B enzymes from a variety of mammals have been reported. One striking feature of these enzymes is their close homology to venom phospholipases of snakes. Mice lacking in PLA2G1B are resistant to obesity and diabetes induced by feeding a diabetogenic high-fat/high-carbohydrate diet. Oral supplementation of a diabetogenic diet with the PLA2G1B inhibitor methyl indoxam effectively suppresses diet-induced obesity and diabetes. PLA2G1B inhibition may be a potentially effective oral therapeutic option for treatment of obesity and diabetes.

纯度:

Greater than 95% as determined by reducing SDS-PAGE.
Endotoxin level less than 0.1 ng/ug (1 IEU/ug) as determined by LAL test.

Accession #:

P04054

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