PMA-其他小分子化合物-深圳欣博盛生物科技有限公司

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PMA

品牌：Adipogen

官网链接

说明书

折扣/货期

货号：AG-CN2-0010-M001	规格：1 mg	目录价：￥456
货号：AG-CN2-0010-M005	规格：5 mg	目录价：￥1296
货号：AG-CN2-0010-M010	规格：10 mg	目录价：￥1920
货号：AG-CN2-0010-M025	规格：25 mg	目录价：￥3600

产品详情

* 以下信息仅供参考，详情请以原厂网站为准

产品名称:

PMA

别名:

PMA; TPA; 12-O-Tetradecanoylphorbol 13-acetate

产品描述:

PMA/TPA is the most commonly-used phorbol ester [1,2]. Binds to and activates protein kinase C (PKC) at nM concentrations [1,2,9]. Induces cell growth arrest through a variety of pathways including the mitogen-activated protein kinases (MAPKs), p38 and c-Jun N-terminal kinase (JNK) pathways mediated by cyclin dependent kinase (CDK) inhibitors such as p21WAF1/CIP1, p27KIP1, p15 and p16. Potent mouse skin tumor promoter [3,4]. Promoter of inducible NOS (iNOS; NOS II) [5]. Apoptosis inducer [6]. Potential effective cancer therapeutic agent [7,8]. Inhibitor of anti-lipolytic activity of insulin [10]. PMA treatment stimulates THP-1 cells and generates M0 macrophages (M0).

宿主来源:

Semisynthetic.

保存温度:

+4°C

运输温度:

Ambient

预期分子量:

616.8

产品形式:

solid

有效期:

Stable for at least 2 years after receipt when stored at -20°C.