货号:CDX-P0933-M050 | 规格:50 mg | 目录价:¥1008 |
产品详情
* 以下信息仅供参考,详情请以原厂网站为准
产品名称:
Pravastatin sodium salt hydrate
别名:
Eptastatin sodium salt; 3beta-Hydroxycompactin; Mevalothin
产品描述:
Pravastatin is a water-soluble, orally effective, competitive inhibitor of Hydroxymethylglutaryl-coenzyme A (HMG-CoA) reductase (Ki = 2.3nM), the rate-limiting enzyme in the cholesterol biosynthetic pathway and the target of the statin class of cholesterol-lowering/regulating compounds. Pravastatin potently blocks cholesterol synthesis in vivo (Ki~ 1 nM) and displays cardioprotective properties. Pravastatin reduces LDL cholesterol and triglyceride levels and increase HDL cholesterol in the prevention of cardiovascular disease. Pravastatin also acts as an immunomodulator and as an inhibitor of p21ras isoprenylation.
宿主来源:
Synthetic.
保存温度:
+20°C
运输温度:
Ambient
预期分子量:
446.51
产品形式:
solid
有效期:
Stable for at least 2 years after receipt when stored at +4°C.
产地:
瑞士
纯度:
> 98% (HPLC)
CAS号:
81131-70-6 (sodium salt) | 81093-37-0 (free acid)
分子式:
C23H35O7Na
溶解度:
Soluble in water (30mg/ml) or DMSO (30mg/ml).
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