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折扣/货期| 货号：11-228 | 规格：0.1 mg | 目录价：￥11547.9 |
产品详情
* 以下信息仅供参考，详情请以原厂网站为准
产品名称:
PSMA / FOLH1 Recombinant Protein
别名:
FOLH1,PSMA,GIG27,FOLH,NAALAD1,PSM,NAALADase I,GCPII,FGCP
实验应用:
ELISA,WB
表达系统:
HEK293 cells
保存温度:
Lyophilized Protein should be stored at -20˚C or lower for long term storage. Upon reconstitution, working aliquots should be stored at -20˚C or -70˚C. Avoid repeated freeze-thaw cycles.
运输温度:
Blue Ice
产品形式:
Lyophilized
存储溶液:
50 mM Tris, 100 mM Glycine, 150 mM NaCl, pH7.5
产地:
美国
生产商:
Prosci
功能与背景:
Prostate-specific membrane antigen (PSMA) is also known as Folate hydrolase 1 (FOLH1), Glutamate carboxypeptidase 2 (GCP2), N-acetylated-alpha-linked acidic dipeptidase I (NAALAD1), which belongs to the peptidase M28 family and M28B subfamily. FOLH1 / PSMA is stable at pH greater than 6.5. FOLH1 / PSMA is a type II transmembrane zinc metallopeptidase that is most highly expressed in the nervous system, prostate, kidney, and small intestine. FOLH1 / GCP-2 is homodimer and binds 2 zinc ions per subunit, and required for NAALADase activity. The catalytic activity of PSMA involved in releasing of an unsubstituted, C-terminal glutamyl residue, typically from Ac-Asp-Glu or folylpoly – gamma - glutamates. FOLH1 / GCP-2 / PSMA has both folate hydrolase and N – acetylated – alpha – linked - acidic dipeptidase (NAALADase) activity and has a preference for tri-alpha-glutamate peptides. GCP-2 / PSMA involved in prostate tumor progression and also exhibits a dipeptidyl-peptidase IV type activity. In vitro, cleaves Gly-Pro-AMC.
纯度:
>95% as determined by SDS-PAGE.
Accession #:
NP_058050.3
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