货号:AG-CR1-3582-M005 | 规格:5 mg | 目录价:¥600 |
货号:AG-CR1-3582-M025 | 规格:25 mg | 目录价:¥2400 |
产品详情
* 以下信息仅供参考,详情请以原厂网站为准
产品名称:
R-848
别名:
Resiquimod; S 28463; R848
产品描述:
Immune response modifier. Potent antitumor and antiviral compound [1, 3, 10, 11, 13, -16]. Stimulates antibody secretion and cytokine production [2]. Used as adjuvant to increase the effectiveness of vaccines [2, 7, 9, 10]. Potent and selective synthetic ligand for Toll-like receptor 7 (TLR7) in mouse and for TLR7 and TLR8 in human [4-6]. Activates immune cells via the TLR7/TLR8 MyD88-dependent signaling pathway and leads to the induction of NF-kappaB [4]. NLRP3/NALP3 inflammasome activator, independent of TLRs and RIG-I [8]. Upregulator of the opioid growth factor receptor [12]. Used in the treatment of skin lesions such as herpes simplex virus [16].
宿主来源:
Synthetic.
保存温度:
+4°C
运输温度:
Ambient
预期分子量:
314.4
产品形式:
solid
有效期:
Stable for at least 2 years after receipt when stored at -20°C. Stock solutions are stable for at least 3 months when stored at -20°C.
产地:
瑞士
纯度:
>98%
CAS号:
144875-48-9
分子式:
C17H22N4O2
溶解度:
Soluble in DMSO, dichloromethane or methanol. Slightly soluble in acetonitrile or ethyl acetate.
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