| 货号:AG-MR-C0001-M025 | 规格:25 mg | 目录价:¥1800 |
产品详情
* 以下信息仅供参考,详情请以原厂网站为准
产品名称:
(R)-Roscovitine
别名:
Seliciclib; CYC201; 6-Benzylamino-2-(R)-[(1-ethyl)-2-hydroxyethylamino]-9-isopropylpurine
产品描述:
Potent and selective inhibitor of cyclin dependent kinases CDK1, CDK2, CDK5, CDK7 and CDK9. Pyridoxal kinase (PDXK) inhibitor. Triggers cell apoptotic cell death. Down-regulates Mcl-1 and MYCN. Anticancer compound. Kills chronic lymphocytic leukemia (LLC) cells and slows tumor growth in mouse xenografts. Inhibits cysts formation in culture and in polycystic kidney disease (PKD) mouse models. Potential anti-inflammatory compound that can influence the resolution of inflammation. Potential antidiabetic compound. Shown to protect pancreatic beta-cells from glucotoxicity and increase insulin secretion. Shows antiviral properties. Neuroprotective in brain trauma. Has positive effects on Timothy syndrome cells. Used for cloning of mammals by synchronization of nucleus donor cells. Provides neuroprotection in experimental traumatic brain injury.
保存温度:
+4°C
运输温度:
Ambient
预期分子量:
354.5
产品形式:
solid
产地:
瑞士
纯度:
>99% (NMR)
CAS号:
186692-46-6
分子式:
C19H26N6O
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