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折扣/货期| 货号：AG-CP3-0044-M001 | 规格：1 mg | 目录价：￥660 |
| 货号：AG-CP3-0044-M005 | 规格：5 mg | 目录价：￥2640 |
| 货号：AG-CP3-0044-M025 | 规格：25 mg | 目录价：￥5760 |
| 货号：AG-CP3-0044-M100 | 规格：100 mg | 目录价：￥16200 |
产品详情
* 以下信息仅供参考，详情请以原厂网站为准
产品名称:
Retatrutide . sodium salt
别名:
LY3437943; GGG Tri-agonist
产品描述:
Retatrutide is a novel triple agonist peptide of the glucagon receptor (GCGR), glucose-dependent insulinotropic polypeptide receptor (GIPR) and glucagon-like peptide-1 receptor (GLP-1R). Retatrutide inhibits human GCGR, GIPR and GLP-1R with EC50 values of 5.79, 0.0643 and 0.775 nM, respectively and mouse GCGR, GIPR, and GLP-1R with EC50 values of 2.32, 0.191 and 0.794 nM, respectively. It is an important tool for obesity research. Retatrutide potently activates the GLP-1R signaling pathway to stimulate glucose-dependent insulin secretion through activity at the GIP receptor (GIPR) or the GLP-1R. Retatrutide is a synthetic peptide with glucose-lowering effects. It is an antidiabetic agent against type 2 diabetes (T2D), stimulating insulin and suppressing glucagon secretion in a glucose-dependent manner. Retatrutide was also shown to delay gastric emptying, lower fasting and postprandial glucose concentration, decrease food intake and reduce body weight in patients with type 2 diabetes.
宿主来源:
Synthetic
保存温度:
+4°C
运输温度:
Ambient
预期分子量:
4731.4 . 23.0
产品形式:
solid
产地:
瑞士
纯度:
>98% (HPLC)
CAS号:
2381089-83-2 (free acid)
分子式:
C221H342N46O68 . Na
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