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折扣/货期| 货号：10-043 | 规格：25 mg | 目录价：￥4264.65 |
产品详情
* 以下信息仅供参考，详情请以原厂网站为准
产品名称:
Ruxolitinib . phosphate salt
别名:
INCB018424; INC 424
保存温度:
Short Term Storage: +4C. Long Term Storage: -20C. Handling Advice: Keep cool and dry. Use/Stability: Stable for at least 2 years after receipt when stored at -20C.
运输温度:
Blue Ice
产品形式:
Lyophilized
产地:
美国
生产商:
Prosci
功能与背景:
Water-soluble phosphate salt of Ruxolitinib. Antineoplastic, anti-inflammatory and immunomodulating agent. Orally bioavailable potent ATP mimetic that inhibits both JAK1 and JAK2 with IC50 values of 2.7 and 4.5nM, respectively and is less selective for JAK3 (IC50=322nM). Affects DC differentiation and function, leading to impaired T cell activation. Used in the treatment of myeloproliferative neoplasms and psoriasis. Anticancer agent. Shown to induce apoptosis and autophagy. Potent and selective inhibitor of HIV-1 replication and virus reactivation in vitro. It is investigated against the spread of the SARS-CoV-2 (COVID-19)
纯度:
greater than or equal to 98% (HPLC)
CAS号:
1092939-17-7
分子式:
C17H18N6 . H3O4P
促销活动
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