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折扣/货期| 货号：CDX-S0377-M010 | 规格：10 mg | 目录价：￥2282 |
| 货号：CDX-S0377-M050 | 规格：50 mg | 目录价：￥6916 |
产品详情
* 以下信息仅供参考，详情请以原厂网站为准
产品名称:
Sanguinarine chloride hydrate
别名:
Sanguinarine hydrochloride
产品描述:
Sanguinarine chloride is a quaternary ammonium benzophenanthine alkaloid found in traditional herbs such as Chelidonium, Corydalis, Sanguinarum, and Borovula. It has been proven to possess broad-spectrum biological activities, such as antitumor, anti-inflammatory, antiosteoporosis, neuroprotective, immune regulatory, cardiovascular, antibacterial, antiviral and antiparasitic activities. Sanguinarine chloride is an inhibitor of protein phosphatase 2C (PP2C), selective over PP1, PP2A and PP2B in vitro. It inhibits mitogen-activated protein kinase phosphatase-1 (MKP-1), JNK, MAPK, NF-kB, STAT3, MMP-2, MMP-9 and other kinases. Sanguinarine chloride blocks cell cycle in the G1 phase, stimulates apoptosis via induction of reactive oxygen species (ROS), disrupts the microtubule assembly and causes DNA damage resulting the death of the cancer cells.
宿主来源:
Semisynthetic
保存温度:
+20°C
运输温度:
Ambient
预期分子量:
367.78 (anhydrous basis)
产品形式:
solid
产地:
瑞士
纯度:
>98% (HPLC)
CAS号:
5578-73-4
分子式:
C20H14ClNO4 . xH2O
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