官网链接
折扣/货期| 货号：SYN-1165-M001 | 规格：1 mg | 目录价：￥2870 |
| 货号：SYN-1165-M005 | 规格：5 mg | 目录价：￥5824 |
| 货号：SYN-1165-M010 | 规格：10 mg | 目录价：￥9142 |
| 货号：SYN-1165-M050 | 规格：50 mg | 目录价：￥询价 |
| 货号：SYN-1165-M100 | 规格：100 mg | 目录价：￥询价 |
产品详情
* 以下信息仅供参考，详情请以原厂网站为准
产品名称:
SAR-131675
别名:
SAR131675
产品描述:
SAR131675 is a potent and selective VEGFR-3 inhibitor. It inhibited VEGFR-3 tyrosine kinase activity and VEGFR-3 autophosphorylation in HEK cells with IC(50) values of 20 and 45nM, respectively. SAR131675 dose dependently inhibited the proliferation of primary human lymphatic cells, induced by the VEGFR-3 ligands VEGFC and VEGFD, with an IC(50) of about 20nM. SAR131675 was found to be highly selective for VEGFR-3 versus 107 receptors, enzymes, ion channels, and 65 kinases. However, it was moderately active on VEGFR-2 with a VEGFR-3/VEGFR-2 ratio of about 10. SAR131675 had no antiproliferative activity on a panel of 30 tumors and primary cells, further showing its high specificity and indicating that SAR131675 is not a cytotoxic or cytostatic agent.
保存温度:
+4°C
运输温度:
Ambient
预期分子量:
358.4
产品形式:
solid
产地:
瑞士
纯度:
>95%
CAS号:
1092539-44-0
分子式:
C18H22N4O4
促销活动
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