| 货号:SD9400 | 规格:1 Set | 目录价:¥7590.375 |
产品详情
* 以下信息仅供参考,详情请以原厂网站为准
产品名称:
SARS-CoV-2 (COVID-19) S1 RBD Detection Set
反应种属:
Virus
宿主来源:
llama
实验应用:
ELISA,ICC
同种型:
sdab
克隆性:
Monoclonal
纯化方式:
Affinity chromatography purified via Nickel column. Antibodies are supplied as a His-tagged purified protein. They also contains a myc-tag for detection.
偶联:
Unconjugated
产品浓度:
Antibody 1 mg/mL
保存温度:
Antibodies should be stored in working aliquots at -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
运输温度:
Dry Ice
产品形式:
Liquid
存储溶液:
PBS containing 0.02% sodium azide.
产地:
美国
生产商:
Prosci
功能与背景:
Coronavirus disease 2019 (COVID-19), formerly known as 2019-nCoV acute respiratory disease, is an infectious disease caused by SARS-CoV-2, a virus closely related to the SARS virus (1). The disease is the cause of the 2019–20 coronavirus outbreak (2). The structure of 2019-nCoV consists of the following: a Spike protein (S), hemagglutinin-esterease dimer (HE), a membrane glycoprotein (M), an envelope protein (E) a nucleoclapid protein (N) and RNA. Coronavirus invades cells through Spike (S) glycoproteins, a class I fusion protein. It is the major viral surface protein that coronavirus uses to bind to the human cell surface receptor. It also mediates the fusion of host and viral cell membrane, allowing the virus to enter human cells and begin infection (3). The spike protein is the major target for neutralizing antibodies and vaccine development (4). The protein modeling suggests that there is strong interaction between Spike protein receptor-binding domain and its host receptor angiotensin-converting enzyme 2 (ACE2), which regulate both the cross-species and human-to-human transmissions of COVID-19 (5). The recent study has shown that the SARS-CoV-2 spike protein binds ACE2 with higher affinity than SARS-CoV spike protein (6).
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