SET7/9 Methyltransferase Inhibitor Screening Assay Kit-抑制剂筛选试剂盒-深圳欣博盛生物科技有限公司

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SET7/9 Methyltransferase Inhibitor Screening Assay Kit

品牌：Cayman

官网链接

说明书

折扣/货期

货号：700270

规格：96 wells

目录价：￥11055

产品详情

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产品名称:

SET7/9 Methyltransferase Inhibitor Screening Assay Kit

别名:

KMT7|SET Domain-containing Protein 7/9|SETD7/9

产品描述:

SET7/9 is an MT that acts on various substrates including histone 3 at lysine residue 4 (H3K4), p53, and the transcription factor TAF 10. Unlike most SET proteins, SET7/9 is exclusively a mono-methylase. Cayman’s SET7/9 MT Inhibitor Screening Assay provides a convenient method for screening SET7/9 inhibitors. The transfer of the methyl group from SAM by SET7/9 to the acceptor peptide (TAF 10) generates SAH, which is rapidly converted to urate and H2O2 using an enzyme mixture provided in the kit. A subsequent reaction between H2O2 and ADHP (10-acetyl-3,7-dihydroxyphenoxazine) produces the highly fluorescent compound resorufin. Resorufin fluorescence is analyzed using an excitation wavelength between 530-540 nm and an emission wavelength between 585-595 nm.

保存温度:

-80

运输温度:

-80

有效期:

730

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