SET8 Methyltransferase Inhibitor Screening Assay Kit-抑制剂筛选试剂盒-深圳欣博盛生物科技有限公司

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SET8 Methyltransferase Inhibitor Screening Assay Kit

品牌：Cayman

官网链接

说明书

折扣/货期

货号：700350

规格：96 wells

目录价：￥11055

产品详情

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产品名称:

SET8 Methyltransferase Inhibitor Screening Assay Kit

别名:

PR-Set7|SET domain-containing (lysine methyltransferase) 8|SETD8

产品描述:

SET Domain-containing Protein 8 is a MT that selectively mono-methylates histone H4 at lysine residue 20 (H4K20), an event proven to have an important role in chromatin structure and transcriptional activation. Cayman’s SET8 MT Inhibitor Screening Assay provides a convenient method for screening human SET8 inhibitors. The transfer of the methyl group from SAM by SET8 (provided in the kit) to the acceptor peptide (H4K20) generates S-adenosylhomocysteine, which is rapidly converted to urate and H2O2 using an enzyme mixture provided in the kit. The H2O2 formed reacts with ADHP (10-acetyl-3,7-dihydroxyphenoxazine) to produce the highly fluorescent compound resorufin (excitation 530-540 nm; emission 585-595 nm).

保存温度:

-80

运输温度:

-80

有效期:

730

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