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折扣/货期| 货号：11-190 | 规格：0.1 mg | 目录价：￥10126.35 |
产品详情
* 以下信息仅供参考，详情请以原厂网站为准
产品名称:
Siglec-10 Recombinant Protein
别名:
SIGLEC10,MGC126774,PRO940,Siglec10,SLG2
实验应用:
WB
表达系统:
HEK293 cells
保存温度:
Lyophilized Protein should be stored at -20˚C or lower for long term storage. Upon reconstitution, working aliquots should be stored at -20˚C or -70˚C. Avoid repeated freeze-thaw cycles.
运输温度:
Blue Ice
产品形式:
Lyophilized
存储溶液:
25 mM MES, 150 mM NaCl, pH5.5
产地:
美国
生产商:
Prosci
功能与背景:
The siglecs (sialic acid-binding Ig-like lectins) are a distinct subset of the Ig superfamily with adhesion-molecule-like structure. We describe here a novel member of the siglec protein family that shares a similar structure including five Ig-like domains, a transmembrane domain, and a cytoplasmic tail containing two ITIM-signaling motifs. Siglec-10 was identified through database mining of an asthmatic eosinophil EST library. The Siglec-10-VAP-1 interaction seems to mediate lymphocyte adhesion to endothelium and has the potential to modify the inflammatory microenvironment via the enzymatic end products.
纯度:
>95% as determined by SDS-PAGE.
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