Silibinin-其他小分子化合物-深圳欣博盛生物科技有限公司

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Silibinin

品牌：Adipogen

官网链接

说明书

折扣/货期

货号：CDX-S0276-G010	规格：10 g	目录价：￥1022
货号：CDX-S0276-G100	规格：100 g	目录价：￥8106

产品详情

* 以下信息仅供参考，详情请以原厂网站为准

产品名称:

Silibinin

别名:

2,3-Dihydro-3-(4-hydroxy-3-methoxyphenyl)-2-(hydroxymethyl)-6-(3,5,7-trihydroxy-4-oxobenzopyran-2-yl)benzodioxin; Silybin; NSC 651520; Flavobin; Silymarin I

产品描述:

Silibinin is a naturally occurring flavanone from Silybum marianum (milk thistle plant) and the main component (active principle) of the Silymarin extract. Silibinin has shown pleiotropic biological properties, including potent antioxidant, anti-inflammatory, anticancer, antidiabetic, hepatoprotective, neuroprotective, antiviral, antimicrobial and immunosuppressive activities. Silibinin demonstrates promising anticancer effects in vitro and in vivo. The molecular mechanisms of silibinin-mediated antiproliferative effects are mainly via receptor tyrosine kinases, androgen receptor, STATs, NF-kappaB, cell cycle arrest and apoptotis/autophagy inducing signaling pathways in various cancer cells. Silibinin was reported to improve glycemic homeostasis by improving the activity of pancreatic beta-cells, increasing insulin sensitivity of liver and muscle cells and decreasing lipid deposition in adipocytes. Next to modulating the NFkappa signaling pathway, Sibilin also inhibits NLRP1/NLRP3 inflammasomes signaling pathways. It modulates many molecular changes caused by xenobiotics and ultraviolet radiation to protect the skin and is used in cosmeceutical preparations.

宿主来源:

Plant

保存温度:

-20°C

运输温度:

Ambient

预期分子量:

482.44

产品形式:

solid

产地:

瑞士