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折扣/货期| 货号：40-455-0.005 mg | 规格：0.005 mg | 目录价：￥3783 |
| 货号：40-455-0.025 mg | 规格：0.025 mg | 目录价：￥5674.5 |
产品详情
* 以下信息仅供参考，详情请以原厂网站为准
产品名称:
Soluble CD40 Ligand Recombinant Protein
别名:
IGM, p50, Bp50, GP39, IMD3, TRAP, HIGM1, T-BAM, Tnfrsf5, AI326936, Tumor necrosis factor receptor superfamily member 5, B-cell surface antigen CD40
表达系统:
E. coli
保存温度:
The lyophilized Soluble CD40 Ligand recombinant protein is stable for at least 2 years from date of receipt at -20˚C. Reconstituted Soluble CD40 Ligand is stable for at least 3 months when stored in working aliquots with a carrier protein at -20˚C. As with any protein, exposing Soluble CD40 Ligand recombinant protein to repeated freeze / thaw cycles is not recommended. When working with proteins care should be taken to keep recombinant protein at a cool and stable temperature.
运输温度:
Blue Ice
产品形式:
Lyophilized
产地:
美国
生产商:
Prosci
功能与背景:
CD40, a member of the TNF receptor family, is a cell surface protein expressed on B cells, dendritic cells, monocytes, thymic epithelial cells and, at low levels, on T cells. Signaling though CD40 plays an important role in the proliferation and differentiation of B cells, and is critical for immunoglobulin (Ig) class switching. The membrane-anchored CD40-Ligand is expressed almost exclusively on activated CD4+ T lymphocytes. Failure to express CD40L leads to "immunodeficiency with hyper-IgM", a disease characterized by failure to produce IgG, IgA and IgE. The soluble form of CD40L is an 18kDa protein comprising the entire TNF homologous region of CD40L and is generated in vivo by an intracellular proteolytic processing of the full length CD40L. Recombinant murine CD40L is a soluble 16.4 kDa protein containing 149 amino acid residues comprising the receptor binding TNF-like domain of CD40L.
纯度:
Greater than 98% by SDS-PAGE gel and HPLC analyses.
Endotoxin level is less than 0.1 ng per μg (1EU/μg).
Endotoxin level is less than 0.1 ng per μg (1EU/μg).
生物活性:
Biological activity was determined by its ability to induce TNF - alpha and MIP - 1 alpha production by murine splenocytes. The expected ED50 for this effect is < 0.1 μg/mL.
Accession #:
NP_035741.2
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