| 货号:AG-CR1-3707-M001 | 规格:1 mg | 目录价:¥360 |
| 货号:AG-CR1-3707-M005 | 规格:5 mg | 目录价:¥600 |
| 货号:AG-CR1-3707-M025 | 规格:25 mg | 目录价:¥840 |
| 货号:AG-CR1-3707-M500 | 规格:500 mg | 目录价:¥3360 |
产品详情
* 以下信息仅供参考,详情请以原厂网站为准
产品名称:
Sunitinib . malate
别名:
SU-11248
产品描述:
Potent ATP-competitive and cell permeable multi-targeted receptor tyrosine kinase (RTK) inhibitor targeting VEGFR and PDGFR-beta. Inhibits FLK1 (Ki=9nM), PDGFRbeta (Ki=8nM) and FLT3. It is at least 10-fold selective for FLK1 and PDGFRbeta over a variety of tyrosine kinases in a panel, including EGFR, Cdk2, Met, IGFR-1, Abl and Src. Inhibits the cellular receptor phosphorylation of FLT3, RET and CSF-1R. Also shown to inhibit c-Kit. Exhibits potent antiangiogenic and antitumor activity in multiple xenograft models.
保存温度:
+4°C
运输温度:
Ambient
预期分子量:
398.5 . 134.1
产品形式:
solid
产地:
瑞士
纯度:
>98%
CAS号:
341031-54-7
分子式:
C22H27FN4O2 . C4H6O5
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