深圳欣博盛生物科技有限公司 a1

Tau-441 / 2N4R Recombinant Protein
品牌:ProSci LLC
货号:11-378 规格:0.1 mg 目录价:¥10126.35
产品详情
* 以下信息仅供参考,详情请以原厂网站为准
产品名称:
Tau-441 / 2N4R Recombinant Protein
别名:
DDPAC,FTDP-17,MAPT,MSTD,MTBT1,Tau,PHF-tau,TAU
实验应用:
WB
表达系统:
E. coli
保存温度:
Lyophilized Protein should be stored at -20˚C or lower for long term storage. Upon reconstitution, working aliquots should be stored at -20˚C or -70˚C. Avoid repeated freeze-thaw cycles.
运输温度:
Blue Ice
产品形式:
Lyophilized
存储溶液:
50 mM Tris, 150 mM NaCl, 1 mM TCEP, 1 mM EDTA, pH7.5
产地:
美国
生产商:
Prosci
功能与背景:
Tau is a microtubule-associated protein, which encodes by the MAPT gene that located on chromosome 17q21. Tau Promotes microtubule assembly and stability, and might be involved in the establishment and maintenance of neuronal polarity. Hyperphosphorylation of the tau protein (tau inclusions, pTau) can result in the self-assembly of tangles of paired helical filaments and straight filaments, which are involved in the pathogenesis of Alzheimer's disease, frontotemporal dementia, and other tauopathies. Tau-441 is known as "2N4R," "Isoform Tau-F," "Tau-4" or "Tau 441", which consisting of 441 amino acid. Tau-441 is a potential therapeutic target for pathogenesis.
纯度:
>90% as determined by reduced SDS-PAGE.
Accession #:
NP_005901.2
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