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折扣/货期| 货号：91-159 | 规格：0.05 mg | 目录价：￥11969.1 |
产品详情
* 以下信息仅供参考，详情请以原厂网站为准
产品名称:
Thimet Oligopeptidase Recombinant Protein
别名:
Thimet Oligopeptidase, Endopeptidase 24.15, MP78, THOP1
表达系统:
E. coli
保存温度:
Store at -20˚C, stable for 6 months after receipt.
Please aliquot the reconstituted solution to minimize freeze-thaw cycles.
Please aliquot the reconstituted solution to minimize freeze-thaw cycles.
运输温度:
Dry Ice
产品形式:
Liquid
存储溶液:
Supplied as a 0.2 um filtered solution of 20mM PB, 100mM NaCl, 10% Glycerol, pH 7.0. It is not recommended to reconstitute to a concentration less than 100 ug/ml.
产地:
美国
生产商:
Prosci
功能与背景:
Thimet Oligopeptidase (THOP1) belongs to the peptidase M3 family which includes neurolysin and mitochondrial intermediate peptidase. THOP1 is located in Cytoplasm. THOP1 is widely expressed in human tissues and can detected in different subcellular locations. THOP1 is preferential cleavage for bonds with hydrophobic residues at P1, P2 and P3' and a small residue at P1' in substrates of 5 to 15 residues. THOP1 is involved in the metabolism of neuropeptides under 20 amino acid residues and degradation of cytoplasmic peptide. In addition, THOP1 also can degrade the beta-amyloid precursor protein and generate amyloidogenic fragments.
纯度:
Greater than 95% as determined by reducing SDS-PAGE.
Endotoxin level less than 0.1 ng/ug (1 IEU/ug) as determined by LAL test.
Endotoxin level less than 0.1 ng/ug (1 IEU/ug) as determined by LAL test.
Accession #:
P52888
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