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折扣/货期| 货号：GTX21654 | 规格：100μg | 目录价：￥5300 |
产品详情
* 以下信息仅供参考，详情请以原厂网站为准
产品名称:
TLR5 antibody
别名:
MELIOS,SLE1,SLEB1,TIL3,TLR5,toll like receptor 5
反应种属:
Human, Mouse
宿主来源:
Goat
实验应用:
ELISA, FCM, IHC-P, WB
靶标/特异性:
Peptide sequence is < 50 % identical to other human TLR receptors in this region.
同种型:
IgG
免疫原:
Synthetic peptide DLSKNQIRSLYLHPSFGKLNSLKSIDFSSNQ corresponding to aa 151-181 of human TLR5
克隆性:
Polyclonal
克隆号:
纯化方式:
Purified by affinity chromatography
偶联:
Unconjugated
产品浓度:
1 mg/ml (Please refer to the vial label for the specific concentration.)
保存温度:
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
运输温度:
4°C
预期分子量:
98
产品形式:
Liquid
存储溶液:
10mM KHPO₄, 140mM NaCl, 0.1% BSA, 0.1% Sodium azide.
生产商:
GeneTex
功能与背景:
This gene encodes a member of the toll-like receptor (TLR) family, which plays a fundamental role in pathogen recognition and activation of innate immune responses. These receptors recognize distinct pathogen-associated molecular patterns that are expressed on infectious agents. The protein encoded by this gene recognizes bacterial flagellin, the principal component of bacterial flagella and a virulence factor. The activation of this receptor mobilizes the nuclear factor NF-kappaB, which in turn activates a host of inflammatory-related target genes. Mutations in this gene have been associated with both resistance and susceptibility to systemic lupus erythematosus, and susceptibility to Legionnaire disease.[provided by RefSeq, Dec 2009]
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