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折扣/货期| 货号：40-609 | 规格：0.05 mg | 目录价：￥6493.5 |
产品详情
* 以下信息仅供参考，详情请以原厂网站为准
产品名称:
TNF-alpha Recombinant Protein
别名:
DIF, TNFA, TNFSF2, TNF-alpha, Tumor necrosis factor, Cachectin, TNF-a
表达系统:
E. coli
保存温度:
The lyophilized TNF-alpha recombinant protein is stable for at least 2 years from date of receipt at -20˚C. Reconstituted TNF-alpha is stable for at least 3 months when stored in working aliquots with a carrier protein at -20˚C. As with any protein, exposing TNF-alpha recombinant protein to repeated freeze / thaw cycles is not recommended. When working with proteins care should be taken to keep recombinant protein at a cool and stable temperature.
运输温度:
Blue Ice
产品形式:
Lyophilized
产地:
美国
生产商:
Prosci
功能与背景:
TNF-a is a pleiotrophic pro-inflammatory cytokine secreted by various cells including adipocytes, activated monocytes, macrophages, B cells, T cells and fibroblasts. It belongs to the TNF family of ligands and signals through two receptors, TNFR1 and TNFR2. TNF-a is cytotoxic to a wide variety of tumor cells and is an essential factor in mediating the immune response against bacterial infections. TNF-a also plays a role in the induction of septic shock, auto immune diseases, rheumatoid arthritis, inflammation, and diabetes. Recombinant human TNF-a is a soluble 157 amino acid protein (17.4 kDa) which corresponds to C-terminal extracellular domain of the full length transmembrane protein.
纯度:
Greater than 98% by SDS-PAGE gel and HPLC analyses.
生物活性:
The ED50as determined by the cytolysis of murine L929 cells in the presence of Actinomyocin D is = 0.05 ng/mL, corresponding to a specific activity of = 2 x 107 units/mg.
Accession #:
NP_000585.2
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