TRAIL Recombinant Protein-其他重组蛋白-深圳欣博盛生物科技有限公司

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TRAIL Recombinant Protein

品牌：ProSci LLC

官网链接

说明书

折扣/货期

货号：91-016

规格：0.05 mg

目录价：￥5756.4

产品详情

* 以下信息仅供参考，详情请以原厂网站为准

产品名称:

TRAIL Recombinant Protein

别名:

Tumor Necrosis Factor Ligand Superfamily Member 10, Apo-2 Ligand, Apo-2L, TNF-Related Apoptosis-Inducing Ligand, Protein TRAIL, CD253, TNFSF10, APO2L, TRAIL

表达系统:

E. coli

保存温度:

Lyophilized protein should be stored at -20˚C, though stable at room temperature for 3 weeks.
Reconstituted protein solution can be stored at 4-7˚C for 2-7 days.
Aliquots of reconstituted samples are stable at -20˚C for 3 months.

运输温度:

Blue Ice

产品形式:

Lyophilized

存储溶液:

Lyophilized from a 0.2 um filtered solution of 150mM NaCl. It is not recommended to reconstitute to a concentration less than 100 ug/ml. Dissolve the lyophilized protein in ddH2O.

产地:

美国

生产商:

Prosci

功能与背景:

Human TNFSF10 is a type II transmembrane protein with an intracellular N-terminus and a ‘TNF homology domain’ (THD) at the extracellular C terminus. TNFSF10 can interact with several distinct receptors. Two of these receptors that belongs to TNFR superfamily, DR4 (TRAIL-R1) and DR5 (TRAIL-R2/TRICK2), are plasma membrane proteins containing intracellular death domains essential for activating apoptosis. TNFSF10 is promising for cancer therapy because it is cytotoxic and activates apoptosis in the majority of malignant cells, but not in normal cells.

纯度:

Greater than 95% as determined by reducing SDS-PAGE.
Endotoxin level less than 0.1 ng/ug (1 IEU/ug) as determined by LAL test.

生物活性:

ED50 is less than 2 ng/ml as determined by the cytolysis of murine L929 cells in the presence of Actinomycin D.
Specific Activity of 5.0 x 10⁶ IU/mg.

Accession #:

P50591

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