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折扣/货期| 货号：AG-CN2-0523-M001 | 规格：1 mg | 目录价：￥960 |
| 货号：AG-CN2-0523-M005 | 规格：5 mg | 目录价：￥2880 |
产品详情
* 以下信息仅供参考，详情请以原厂网站为准
产品名称:
Trichostatin A (synthetic)
别名:
TSA; A300; R-(E,E)-7-(4-(Dimethylamino)phenyl)-N-hydroxy- 4,6-dimethyl-7-oxo-2,4-heptadienamide
产品描述:
Antibiotic, antifungal and antiprotozoal agent. Potent and reversible, cell permeable inhibitor of class I and II histone deacetylases (HDACs). Anticancer, immunosuppressive, antifibrogenic compound. Induces apoptosis and cell growth arrest at both G1 and G2/M phases. Also inactivates mitotic spindle checkpoint. Enhances the efficacy of anticancer agents that target DNA. Downregulates DNA methyltransferase DNMT1 and affects DNA methylation. Telomerase inhibitor. Smooth muscle cell proliferation inhibitor. Anti-inflammatory and inhibits osteoclastogenesis and bone resorption. Promotes either self-renewal or differentiation of embryonic stem cells.
宿主来源:
Synthetic. Originally isolated from Streptomyces hygroscopicus.
保存温度:
+4°C
运输温度:
Ambient
预期分子量:
302.4
产品形式:
solid
有效期:
Stable for at least 3 years after receipt when stored at -20°C.
产地:
瑞士
纯度:
>95% (HPLC)
CAS号:
58880-19-6
分子式:
C17H22N2O3
溶解度:
Soluble in DMSO, ethanol, methanol, dimethyl formamide, acetonitrile or chloroform. Insoluble in water or hexane.
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