深圳欣博盛生物科技有限公司 a1

货号:GTX48720 规格:50μg 目录价:¥5300
产品详情
* 以下信息仅供参考,详情请以原厂网站为准
产品名称:
Trkct1 antibody
别名:
neurotrophic tyrosine kinase, receptor, type 3 , AW125844 , Ntrk3_tv3 , TrkC
反应种属:
Human, Mouse
宿主来源:
Rabbit
实验应用:
ELISA, IP, WB
同种型:
IgG
免疫原:
Synthetic peptide corresponding to amino acids near the carboxyl terminus of mouse TrkCT1 protein.
克隆性:
Polyclonal
克隆号:
纯化方式:
Purified by antigen-affinity chromatography.
偶联:
Unconjugated
产品浓度:
1 mg/ml (Please refer to the vial label for the specific concentration.)
保存温度:
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
运输温度:
4°C
预期分子量:
93
产品形式:
Liquid
存储溶液:
20mM Potassium Phosphate, 150mM NaCl, 0.01% Sodium azide.
生产商:
GeneTex
功能与背景:
TrkCT1, also named neurotrophic tyrosine kinase receptor type 3 (Ntrk3) non-catalytic isoform 2, is a non-catalytic isoform of TrkC, the high affinity receptor for Neurotrophin-3 (NT-3). This isoform lacks the kinase domain that is responsible for signaling by the full-length isoform. TrkCT1 is the product of an alternative splicing of Ntrk3 that leaves the extracellular and transmembrane domains intact but includes a shorter intracellular domain encoded by exons 13b and 14b. Recent studies indicate that the short cytoplasmic tail binds the scaffold protein Tamalin in a ligand-dependent manner and further activates the Arf6–Rac1 signaling pathway (Esteban et al., 2006).
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