TSLP Recombinant Protein-其他重组蛋白-深圳欣博盛生物科技有限公司

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TSLP Recombinant Protein

品牌：ProSci LLC

官网链接

说明书

折扣/货期

货号：40-294-0.002 mg	规格：0.002 mg	目录价：￥3783
货号：40-294-0.01 mg	规格：0.01 mg	目录价：￥5674.5

产品详情

* 以下信息仅供参考，详情请以原厂网站为准

产品名称:

TSLP Recombinant Protein

别名:

Thymic stromal lymphopoietin

表达系统:

E. coli

保存温度:

The lyophilized TSLP recombinant protein is stable for at least 2 years from date of receipt at -20˚C. Reconstituted TSLP is stable for at least 3 months when stored in working aliquots with a carrier protein at -20˚C. As with any protein, exposing TSLP recombinant protein to repeated freeze / thaw cycles is not recommended. When working with proteins care should be taken to keep recombinant protein at a cool and stable temperature.

运输温度:

Blue Ice

产品形式:

Lyophilized

产地:

美国

生产商:

Prosci

功能与背景:

TSLP is a hemopoietic protein that is expressed in the heart, liver and prostate. TSLP overlaps biological activities with IL-7 and binds with the heterodimeric receptor complex consisting of the IL-7R alpha chain (IL-7Rα) and the TSLP-specific chain (TSLPR). Like IL-7, TSLP induces phosphorylation of STAT3 and STAT5, but uses kinases other than the JAKs for activation. TSLP prohibited apoptosis and stimulated growth of the human acute myeloid leukemia (AML)-derived cell line MUTZ3. It induces the release of T cell-attracting chemokines TARC and MDC from monocytes and activates CD11c(+) dendritic cells (DCs). TSLP activated DCs primed naïve T cells to produce the proallergic cytokines (IL-4, IL-5, IL-13, TNFα) while down-regulating IL-10 and IFN-γ suggesting a role in initiating allergic inflammation. Recombinant human TSLP is a 15.0 kDa protein consisting of 132 amino acid residues.

纯度:

Greater than 98% by SDS-PAGE gel and HPLC analyses.

Endotoxin level is less than 0.1 ng per μg (1EU/μg).

Accession #:

NP_149024.1

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